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Abilify is designed for sufferers with analysis named schizophrenia and bipolar affective disorders. It is used either at some stage in the exacerbation duration or for maintenance treatment. Abilify is also prescribed in cases of acute manic episodes of type 1 in manic-depressive psychosis and as a supportive remedy. Abilify can be used as an additional treatment for the duration of depressive disorders. According to some experts, the drug can be used to treat alcoholism.

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Uses

Common use

Abilify is an add-on remedy used for the treatment of the main depressive sickness, schizophrenia, manic, and combined episodes associated with the bipolar ailment in adults and kids and teens and also of irritability associated with autistic disease in pediatric sufferers. The mechanism of the movement of Abilify is unknown. It suggests partial agonism at the D2 receptor. It is likewise a partial agonist at the 5-HT1A receptor and additionally displays an antagonist profile on the 5-HT2A receptor. It has a slight affinity for histamine and alpha-adrenergic receptors, and no considerable affinity for cholinergic muscarinic receptors.



Dosage and direction

Take Abilify as soon as each day with or without food. The standard starting dose is 10 or 15 mg, and later the dose may be expanded to obtain the desired effect.




Contraindications

Breastfeeding, hypersensitivity.



Possible aspect effect

The most common detrimental effects encompass nausea, vomiting, constipation, headache, dizziness, nervousness, sleeplessness, restlessness, tremors, cough, headache, insomnia, lightheadedness, rash, runny nose, weakness, and weight gain. More severe and uncommon unfavorable reactions such as an extended threat of stroke and ministroke; neuroleptic malignant syndrome (NMS), which signs include fever, rigid muscles, confusion, tardive dyskinesia (TD), which symptoms encompass uncontrolled and strange movements of body parts.



Drug interaction

Inform your doctor approximately all prescribed and over-the-counter medicines and herbal products you are taking and especially in case you use alcohol, blood stress tablets, carbamazepine, fluoxetine, ketoconazole, paroxetine, and quinidine.

Carbamazepine (Tegretol) decreases the stages of Abilifyole in the body, stimulating the liver enzymes, including CYP3A4. A comparable influence on Abilify is shown with the aid of phenytoin (Dilantin), rifampin (Rifadin, Rimactane, Rifadin, Rifater, Rifamate), and phenobarbital. Blocking of CYP3A4 via Ketoconazole (Nizoral) increases the quantity of Abilify within the frame. Other capsules with similar action are itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), cimetidine (Tagamet), verapamil (Calan, Isoptin), diltiazem (Cardizem, Dilacor), erythromycin, clarithromycin (Biaxin), nefazodone (Serzone), ritonavir (Norvir), saquinavir (Invirase), nelfinavir (Viracept), indinavir (Crixivan), and grapefruit juice. Their movement isn't well studied, though.

Quinidine (Quinaglute, Quinidex) inhibits any other liver enzyme called CYP2D6 and also can grow the levels of Abilify. Other medicines with comparable motion are fluoxetine (Prozac) and paroxetine (Paxil). Abilify may additionally dangerously boom blood sugar stages in sufferers with diabetes.




Missed dose

Abilify is taken once each day, so take the missed dose as soon as you remember. If the next dose is inside 12 hours, do now not make the ignored dose and resume your regular dosing schedule. Never double the remedy of this medicinal drug.



Storage

Store at room temperature in a tight, dry box out of attaining of youngsters and pets. Do now not use it after the expiration term.

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